1-Phosphatidylinositol 3-Kinase |
| PI 3-Kinase; PI-3K; PI-3K Isotype p110 gamma; PI3-Kinase; Phosphoinositide 3-Hydroxykinase; Vps34 Phosphatidylinositol 3-Kinase; alpha-P85 Subunit, PI-3K; p110 gamma; 1 Phosphatidylinositol 3 Kinase; 3-Hydroxykinase, Phosphoinositide |
| An enzyme that catalyzes the conversion of phosphatidylinositol to phosphatidylinositol 3-phosphate. This is the first committed step in the biosynthesis of phosphatidylinositol 3,4-bisphosphate and phosphatidylinositol 3,4,5-trisphosphate. This pathway is thought to play a critical role in DNA repair, V(D)J recombination and cell cycle checkpoints. EC 2.7.1.137. |
|
|
|