14-3-3 Proteins |
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| 14-3-3 Protein; 14-3-3 Protein, beta Isoform; 14-3-3 Protein, epsilon Isoform; 14-3-3 Protein, eta Isoform; 14-3-3 Protein, gamma Isoform; 14-3-3 Protein, tau Isoform; 14-3-3 Protein, zeta Isoform; 14-3-3 beta Protein; 14-3-3 epsilon Protein | |
| A large family of signal-transducing adaptor proteins present in wide variety of eukaryotes. They are PHOSPHOSERINE and PHOSPHOTHREONINE binding proteins involved in important cellular processes including SIGNAL TRANSDUCTION; CELL-CYCLE control; APOPTOSIS; and cellular stress responses. 14-3-3 proteins function by interacting with other signal-transducing proteins and effecting changes in their enzymatic activity and subcellular localization. The name 14-3-3 derives from numerical designations used in the original fractionation patterns of the proteins. | |