5-Aminolevulinate Synthetase |
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| delta-Aminolevulinic Acid Synthetase; 5 Aminolevulinate Synthetase; Acid Synthetase, Aminolevulinic; Acid Synthetase, delta-Aminolevulinic; Synthase, delta-Aminolevulinate; Synthetase, 5-Aminolevulinate; Synthetase, Aminolevulinic Acid | |
| An enzyme of the transferase class that catalyzes condensation of the succinyl group from succinyl coenzyme A with glycine to form delta-aminolevulinate. It is a pyridoxyal phosphate protein and the reaction occurs in mitochondria as the first step of the heme biosynthetic pathway. The enzyme is a key regulatory enzyme in heme biosynthesis. In liver feedback is inhibited by heme. EC 2.3.1.37. | |