Addison Disease

Addison's Disease; Primary Adrenal Insufficiency; Primary Adrenocortical Insufficiency; Primary Hypoadrenalism; Addisons Disease; Adrenal Insufficiency, Primary; Adrenocortical Insufficiencies, Primary; Adrenocortical Insufficiency, Primary
An adrenal disease characterized by the progressive destruction of the ADRENAL CORTEX, resulting in insufficient production of ALDOSTERONE and HYDROCORTISONE. Clinical symptoms include ANOREXIA; NAUSEA; WEIGHT LOSS; MUSCLE WEAKNESS; and HYPERPIGMENTATION of the SKIN due to increase in circulating levels of ACTH precursor hormone which stimulates MELANOCYTES.