Aldosterone Synthase

Aldosterone Synthase Cytochrome P-450; Aldosynthase; CYP 11B2; Cyctochrome P-450 c11AS; Cytochrome P-450c11AS; Cytochrome P450 11B2; Cytochrome P450Aldo; P450c11AS; Cytochrome P 450 CYP11B2; Cytochrome P 450c11AS; Steroid 18 Hydroxylase
A mitochondrial cytochrome P450 enzyme that catalyzes the 18-hydroxylation of steroids in the presence of molecular oxygen and NADPH-specific flavoprotein. This enzyme, encoded by CYP11B2 gene, is important in the conversion of CORTICOSTERONE to 18-hydroxycorticosterone and the subsequent conversion to ALDOSTERONE.