Alzheimer Disease |
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| Alzheimer Disease, Early Onset; Alzheimer Disease, Late Onset; Alzheimer Type Senile Dementia; Alzheimer's Disease; Alzheimer's Disease, Focal Onset; Dementia, Presenile; Dementia, Primary Senile Degenerative; Early Onset Alzheimer Disease | |
| A degenerative disease of the BRAIN characterized by the insidious onset of DEMENTIA. Impairment of MEMORY, judgment, attention span, and problem solving skills are followed by severe APRAXIAS and a global loss of cognitive abilities. The condition primarily occurs after age 60, and is marked pathologically by severe cortical atrophy and the triad of SENILE PLAQUES; NEUROFIBRILLARY TANGLES; and NEUROPIL THREADS. (From Adams et al., Principles of Neurology, 6th ed, pp1049-57) | |