Antigens, CD80 |
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| Antigen, B7; Antigen, B7-1; B7 Antigen; B7-1 Antigen; CD80 Antigen; Antigen, B7 1; B Cell Activation Antigen; B7 1 Antigen; B7 1 Costimulatory Molecule; Costimulatory Molecule, B7-1 | |
| The natural ligand for the T-cell antigen CD28; (ANTIGENS, CD28); mediating T- and B-cell adhesion. CD80 is expressed on activated B-cells and gamma-interferon-stimulated monocytes. The binding of CD80 to CD28 and CTLA-4 provides a co-stimulatory signal to T-cells and leads to greatly upregulated lymphokine production. | |