Antigens, Polyomavirus Transforming |
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| Polyomaviruses Large T Proteins; Polyomaviruses Middle T Proteins; Polyomaviruses Small T Proteins; Antigens, Polyomavirus Tumor; Antigens, SV40 T; Proteins, Polyomavirus T; Proteins, SV40 T; T Antigens, SV40; T Proteins, Polyomavirus; T Proteins, SV40 | |
| Polyomavirus antigens which cause infection and cellular transformation. The large T antigen is necessary for the initiation of viral DNA synthesis, repression of transcription of the early region and is responsible in conjunction with the middle T antigen for the transformation of primary cells. Small T antigen is necessary for the completion of the productive infection cycle. | |