Arachidonate 12-Lipoxygenase

Arachidonic Acid 12-Lipoxygenase; 12 Lipoxygenase; 12-Lipoxygenase, Arachidonate; 12-Lipoxygenase, Arachidonic Acid; Arachidonate 12 Lipoxygenase; Arachidonic Acid 12 Lipoxygenase
An enzyme that catalyzes the oxidation of arachidonic acid to yield 12-hydroperoxyarachidonate (12-HPETE) which is itself rapidly converted by a peroxidase to 12-hydroxy-5,8,10,14-eicosatetraenoate (12-HETE). The 12-hydroperoxides are preferentially formed in platelets. EC 1.13.11.31.