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Arachidonate 5-Lipoxygenase
Arachidonic Acid 5-Lipoxygenase; LTA4 Synthase; Leukotriene A Synthase; Leukotriene A4 Synthase; Leukotriene A4 Synthetase; 5 Lipoxygenase; 5-Lipoxygenase, Arachidonate; 5-Lipoxygenase, Arachidonic Acid; Arachidonate 5 Lipoxygenase
An enzyme that catalyzes the oxidation of arachidonic acid to yield 5-hydroperoxyarachidonate (5-HPETE) which is rapidly converted by a peroxidase to 5-hydroxy-6,8,11,14-eicosatetraenoate (5-HETE). The 5-hydroperoxides are preferentially formed in leukocytes. EC 1.13.11.34.