Calreticulin |
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| 55-kDa High-Affinity Calcium Binding Protein; CAB-63; CBP3 (Liver); Calcium-Binding Protein-3; Calregulin; ERp60; HACBP; cC1qR Protein; 55 kDa High Affinity Calcium Binding Protein; Calcium Binding Protein 3 | |
| A multifunctional protein that is found primarily within membrane-bound organelles. In the ENDOPLASMIC RETICULUM it binds to specific N-linked oligosaccharides found on newly-synthesized proteins and functions as a MOLECULAR CHAPERONE that may play a role in PROTEIN FOLDING or retention and degradation of misfolded proteins. In addition calreticulin is a major storage form for CALCIUM and functions as a calcium-signaling molecule that can regulate intracellular calcium HOMEOSTASIS. | |