Cholesterol 7-alpha-Hydroxylase |
| CYP 7; CYP 7A; Cholesterol 7-alpha-Monooxygenase; Cholesterol 7alpha-Hydroxylase; Cholesterol-7-Hydroxylase; Cytochrome P450 7; Cholesterol 7 Hydroxylase; Cholesterol 7 alpha Hydroxylase; Cholesterol 7 alpha Monooxygenase; Cholesterol 7alpha Hydroxylase |
| A membrane-bound cytochrome P450 enzyme that catalyzes the 7-alpha-hydroxylation of CHOLESTEROL in the presence of molecular oxygen and NADPH-FERRIHEMOPROTEIN REDUCTASE. This enzyme, encoded by CYP7, converts cholesterol to 7-alpha-hydroxycholesterol which is the first and rate-limiting step in the synthesis of BILE ACIDS. |
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