Medical.Webends.com - A B C D E F G H I J K L M N O P Q R S T U V W X Y Z #

Complement Factor I
C3b Inactivator; C3b-C4b Inactivator; C4b-C3b-INA; C4bC3bINA; Complement 3b-Complement 4b Inactivator; Complement C4b-C3b Inactivator; C3b C4b Inactivator; C4b C3b INA; C4b-C3b Inactivator, Complement; Complement 3b Complement 4b Inactivator
A plasma serine proteinase that cleaves the alpha-chains of C3b and C4b in the presence of the cofactors COMPLEMENT FACTOR H and C4-binding protein, respectively. It is a 66-kDa glycoprotein that converts C3b to inactivated C3b (iC3b) followed by the release of two fragments, C3c (150-kDa) and C3dg (41-kDa). It was formerly called KAF, C3bINF, or enzyme 3b inactivator.