Dopamine and cAMP-Regulated Phosphoprotein 32 definition

Dopamine and cAMP-Regulated Phosphoprotein 32
DARPP-32 Protein; Dopamine and Adenosine 3',5'-Monophosphate-Regulated Phosphoprotein; Dopamine and cAMP-Regulated Phosphoprotein; Dopamine- and Cyclic AMP-Regulated Phosphoprotein Mr 32,000; DARPP 32 Protein
A phosphoprotein that was initially identified as a major target of DOPAMINE activated ADENYLYL CYCLASE in the CORPUS STRIATUM. It regulates the activities of PROTEIN PHOSPHATASE-1 and PROTEIN KINASE A, and it is a key mediator of the biochemical, electrophysiological, transcriptional, and behavioral effects of DOPAMINE.