Farnesyl-Diphosphate Farnesyltransferase
FPP-FPP Farnesyl Transferase; Farnesyldiphosphate-Farnesyldiphosphate Farnesyltransferase; Presqualene-Diphosphate Synthase; Squalene Synthase; FPP FPP Farnesyl Transferase; Farnesyl Diphosphate Farnesyltransferase; Farnesyl Transferase, FPP-FPP
The first committed enzyme of the biosynthesis pathway that leads to the production of STEROLS. it catalyzes the synthesis of SQUALENE from FARNESYL PYROPHOSPHATE via the intermediate PRESQUALENE PYROPHOSPHATE. This enzyme is also a critical branch point enzyme in the biosynthesis of ISOPRENOIDS that is thought to regulate the flux of ISOPRENE intermediates through the sterol pathway.