Fibrinogen |
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| Blood Coagulation Factor I; gamma-Fibrinogen; Factor I, Coagulation; I, Coagulation Factor; gamma Fibrinogen | |
| Plasma glycoprotein clotted by thrombin, composed of a dimer of three non-identical pairs of polypeptide chains (alpha, beta, gamma) held together by disulfide bonds. Fibrinogen clotting is a sol-gel change involving complex molecular arrangements: whereas fibrinogen is cleaved by thrombin to form polypeptides A and B, the proteolytic action of other enzymes yields different fibrinogen degradation products. | |