GRB2 Adaptor Protein |
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| Abundant Src Homology Protein; GRB2 Adaptor Protein, Grb3-3 Isoform; Grb3-3 Adaptor Protein; GRB2 Adaptor Protein, Grb3 3 Isoform; Growth Factor Receptor Bound Protein 2 | |
| A signal transducing adaptor protein that links extracellular signals to the MAP KINASE SIGNALING SYSTEM. Grb2 associates with activated EPIDERMAL GROWTH FACTOR RECEPTOR and PLATELET-DERIVED GROWTH FACTOR RECEPTORS via its SH2 DOMAIN. It also binds to and translocates the SON OF SEVENLESS PROTEINS through its SH3 DOMAINS to activate PROTO-ONCOGENE PROTEIN P21(RAS). | |