Genes, myb |
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| c-myb Proto-Oncogenes; myb Oncogene; v-myb Oncogenes; Gene, c-myb; Gene, myb; Gene, v-myb; Genes, c-myb; Genes, v-myb; Oncogene, myb; Oncogene, v-myb; Oncogenes, myb; Oncogenes, v-myb; Proto-Oncogene, c-myb; Proto-Oncogenes, c-myb; c myb Genes | |
| Retrovirus-associated DNA sequences (v-myb) originally isolated from the avian myeloblastosis and E26 leukemia viruses. The proto-oncogene c-myb codes for a nuclear protein involved in transcriptional regulation and appears to be essential for hematopoietic cell proliferation. The human myb gene is located at 6q22-23 on the short arm of chromosome 6. This is the point of break in translocations involved in T-cell acute lymphatic leukemia and in some ovarian cancers and melanomas. (From Ibelgaufts, Dictionary of Cytokines, 1995). | |