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Genes, myc
L-myc Proto-Oncogenes; N-myc Proto-Oncogenes; c-myc Proto-Oncogenes; myc Oncogene; v-myc Oncogenes; Gene, L-myc; Gene, N-myc; Gene, c-myc; Gene, myc; Gene, v-myc; Genes, L-myc; Genes, N-myc; Genes, c-myc; Genes, v-myc; L myc Genes; L myc Proto Oncogenes
Family of retrovirus-associated DNA sequences (myc) originally isolated from an avian myelocytomatosis virus. The proto-oncogene myc (c-myc) codes for a nuclear protein which is involved in nucleic acid metabolism and in mediating the cellular response to growth factors. Truncation of the first exon, which appears to regulate c-myc expression, is crucial for tumorigenicity. The human c-myc gene is located at 8q24 on the long arm of chromosome 8.