Giant Cells, Langhans |
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| Langhans-Type Giant Cells; Cells, Langhans Giant; Cells, Langhans-Type Giant; Giant Cells, Langhans-Type; Langhans Type Giant Cells | |
| Multinucleated cells (fused macrophages) seen in granulomatous inflammations such as tuberculosis, syphilis, sarcoidosis, and deep fungal infections. They resemble foreign-body giant cells (GIANT CELLS, FOREIGN BODY) but Langhans giant cells contain less chromatin and their nuclei are arranged peripherally in a horseshoe-shaped pattern. Langhans giant cells occur frequently in delayed hypersensitivity. | |