Histamine H1 Antagonists, Non-Sedating |
| H1 Antihistamines, Non-Sedating; Second Generation Antihistamines; Second Generation H1 Antagonists; Antihistamines, Second Generation; H1 Antihistamines, Non Sedating; Histamine H1 Antagonists, Non Sedating; Non-Sedating H1 Antihistamines |
| A class of non-sedating drugs that bind to but do not activate histamine receptors, thereby blocking the actions of histamine or histamine agonists. These antihistamines represent a heterogenous group of compounds with differing chemical structures, adverse effects, distribution, and metabolism. Compared to the early (first generation) antihistamines, these non-sedating antihistamines have greater receptor specificity, lower penetration of BLOOD-BRAIN BARRIER, and are less likely to cause drowsiness or psychomotor impairment. |
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