I-kappa B Proteins

I kappa B; I-kappa B; IkB DNA-Binding Proteins; I kappa B Proteins; IkB DNA Binding Proteins
A family of inhibitory proteins which bind to the REL PROTO-ONCOGENE PROTEINS and modulate their activity. In the CYTOPLASM, I-kappa B proteins bind to the transcription factor NF-KAPPA B. Cell stimulation causes its dissociation and translocation of active NF-kappa B to the nucleus.