Immunoglobulin Fab Fragments
Fab Immunoglobulin Fragments; Immunoglobulin Fab Fragment; Immunoglobulins, Fab; Fab Fragment Immunoglobulins; Fab Fragment, Immunoglobulin; Fab Fragments, Immunoglobulin; Fragment Immunoglobulins, Fab; Immunoglobulin Fragments, Fab
Univalent antigen-binding fragments composed of one entire IMMUNOGLOBULIN LIGHT CHAIN and the amino terminal end of one of the IMMUNOGLOBULIN HEAVY CHAINS from the hinge region, linked to each other by disulfide bonds. Fab contains the variable regions of the immunoglobulin molecule, which are part of the antigen-binding site, and the first constant regions. This fragment can be obtained by digestion of immunoglobulins with the proteolytic enzyme PAPAIN.