Immunoglobulin Variable Region
Framework Region, Immunoglobulin; Ig Framework Region; Ig Variable Region; Immunoglobulin Framework Region; Immunoglobulin V; Framework Region, Ig; Framework Regions, Ig; Framework Regions, Immunoglobulin; Ig Framework Regions; Ig Variable Regions
That region of the immunoglobulin molecule that varies in its amino acid sequence and composition, and comprises the binding site for a specific antigen. It is located at the N-terminus of the Fab fragment of the immunoglobulin. It includes hypervariable regions (COMPLEMENTARITY DETERMINING REGIONS) and framework regions.