Inositol 1,4,5-Trisphosphate definition

Inositol 1,4,5-Trisphosphate
1,4,5-IP3; Myoinositol 1,4,5-Triphosphate
Intracellular messenger formed by the action of phospholipase C on phosphatidylinositol 4,5-bisphosphate, which is one of the phospholipids that make up the cell membrane. Inositol 1,4,5-trisphosphate is released into the cytoplasm where it releases calcium ions from internal stores within the cell's endoplasmic reticulum. These calcium ions stimulate the activity of B kinase or calmodulin.