Insulin-Like Growth Factor I definition

Insulin-Like Growth Factor I
IGF-1; IGF-I-SmC; Insulin Like Growth Factor I; Insulin-Like Somatomedin Peptide I; Insulin Like Somatomedin Peptide I
A well-characterized basic peptide believed to be secreted by the liver and to circulate in the blood. It has growth-regulating, insulin-like, and mitogenic activities. This growth factor has a major, but not absolute, dependence on GROWTH HORMONE. It is believed to be mainly active in adults in contrast to INSULIN-LIKE GROWTH FACTOR II, which is a major fetal growth factor.