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Integrin alpha6beta4
A9 Antigen; Integrin alpha(6),beta(4); Laminin-5 Receptor (alpha6beta4 Integrin); TSP-180; Tumor Specific Protein-180 Complex; alpha(6)beta(4) Epithelial Integrin; alpha(6)beta(4) Integrin; alpha6 beta4 Integrin; Antigen, A9; Integrin, alpha6 beta4
This intrgrin is a key component of HEMIDESMOSOMES and is required for their formation and maintenance in epithelial cells. Integrin alpha6beta4 is also found on thymocytes, fibroblasts, and Schwann cells, where it functions as a laminin receptor (RECEPTORS, LAMININ) and is involved in wound healing, cell migration, and tumor invasiveness.