Interferon Regulatory Factor-3 |
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| IFN-Regulatory Factor 3; IFN Regulatory Factor 3; IRF 3 Transcription Factor; Interferon Regulatory Factor 3; Transcription Factor, IRF-3 | |
| An interferon regulatory factor that is expressed constitutively and undergoes POST-TRANSLATIONAL MODIFICATION following viral infection. PHOSPHORYLATION of IRF-3 causes the protein to be translocated from the CYTOPLASM to CELL NUCLEUS where it binds DNA, and activates transcription. | |