Laron Syndrome |
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| Growth Hormone Receptor Defect; Laron Dwarfism; Laron Type Dwarfism I; Primary GH Resistance; Primary Growth Hormone Resistance; Severe GH Insensitivity; Dwarfism, Laron; GH Resistance, Primary; Syndrome, Laron | |
| An autosomal recessive disorder characterized by short stature, defective GROWTH HORMONE RECEPTOR, and failure to generate INSULIN-LIKE GROWTH FACTOR I by GROWTH HORMONE. Laron syndrome is not a form of primary pituitary dwarfism (GROWTH HORMONE DEFICIENCY DWARFISM) but the result of mutation of the human GHR gene on chromosome 5. | |