Leukotriene C4

Leukotriene C; Leukotriene C-1; Leukotriene C-4; Leukotriene C1; Leukotrienes C; Leukotriene C 1; Leukotriene C 4
The conjugation product of LEUKOTRIENE A4 and glutathione. It is the major arachidonic acid metabolite in macrophages and human mast cells as well as in antigen-sensitized lung tissue. It stimulates mucus secretion in the lung, and produces contractions of nonvascular and some vascular smooth muscle. (From Dictionary of Prostaglandins and Related Compounds, 1990)