Mitogen-Activated Protein Kinase 1 |
| ERK2 Brain Kinase PK40; MAPK1 Mitogen-Activated Protein Kinase; MAPK2 Mitogen-Activated Protein Kinase; p40 Mitogen-Activated Protein Kinase; p41 Mitogen-Activated Protein Kinase; p42(Mapk); p42(Mapk) Kinase; Extracellular Signal Regulated Kinase 2 |
| A proline-directed serine/threonine protein kinase which mediates signal transduction from the cell surface to the nucleus. Activation of the enzyme by phosphorylation leads to its translocation into the nucleus where it acts upon specific transcription factors. p40 MAPK and p41 MAPK are isoforms. |
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