Muromonab-CD3 |
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| Cilag Brand of Muromonab-CD3; Janssen Brand of Muromonab-CD3; OKT3; Ortho Brand of Muromonab-CD3; Orthoclone OKT3; Cilag Brand of Muromonab CD3; Janssen Brand of Muromonab CD3; Muromonab CD3; Ortho Brand of Muromonab CD3 | |
| Anti-CD3 monoclonal antibody that exerts immunosuppressive effects by inducing peripheral T-cell depletion and modulation of the T-cell receptor complex (CD3/Ti). This biochemically purified IMMUNOGLOBULIN G is obtained through the fusion of mouse myeloma cells to lymphocytes from immunized animals to produce hybridomas that secrete specific antibodies to the T3 (CD3) antigens of human T-lymphocytes. It is often used as an IMMUNOSUPPRESSIVE AGENTS in TRANSPLANTATION. | |