Nucleic Acid Heteroduplexes |
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| Heteroduplex DNA; Acid Heteroduplexes, Nucleic; DNA, Heteroduplex | |
| Double-stranded nucleic acid molecules (DNA-DNA or DNA-RNA) which contain regions of nucleotide mismatches (non-complementary). In vivo, these heteroduplexes can result from mutation or genetic recombination; in vitro, they are formed by nucleic acid hybridization. Electron microscopic analysis of the resulting heteroduplexes facilitates the mapping of regions of base sequence homology of nucleic acids. | |