Oncogene Protein pp60(v-src) |
| Avian Sarcoma Virus-Transforming Protein; Oncogene Protein src; Phosphoprotein pp60(v-src); Rous Sarcoma Virus-Transforming Protein pp60(v-src); p60(v-src); pp60 v-src; src Oncogene Product pp60; v-src Protein; Avian Sarcoma Virus Transforming Protein |
| A tyrosine-specific protein kinase encoded by the v-src oncogene of Rous sarcoma virus. The transforming activity of pp60(v-src) depends on both the lack of a critical carboxy-terminal tyrosine phosphorylation site at position 527, and the attachment of pp60(v-src) to the plasma membrane which is accomplished by myristylation of its N-terminal glycine. |
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