Osteocalcin |
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| 4-Carboxyglutamic Protein, Bone; Bone gamma-Carboxyglutamic Acid Protein; 4 Carboxyglutamic Protein, Bone; Bone 4-Carboxyglutamic Protein; Bone gamma Carboxyglutamic Acid Protein; Calcium Binding Protein, Vitamin K Dependent | |
| Vitamin K-dependent calcium-binding protein synthesized by OSTEOBLASTS and found primarily in BONES. Serum osteocalcin measurements provide a noninvasive specific marker of bone metabolism. The protein contains three residues of the amino acid gamma-carboxyglutamic acid (Gla), which, in the presence of CALCIUM, promotes binding to HYDROXYAPATITE and subsequent accumulation in BONE MATRIX. | |