Osteogenesis Imperfecta |
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| Lobstein's Disease; Disease, Lobstein; Disease, Lobstein's; Lobsteins Disease; Ossiums, Fragilitas | |
| Autosomal dominant COLLAGEN DISEASES resulting from defective biosynthesis of COLLAGEN TYPE I and characterized by brittle, osteoporotic, and easily fractured bones. It may also present with blue sclerae, loose joints, and imperfect dentin formation. There are four major types, I-IV. | |