P-Glycoprotein |
|
| ATP-Binding Cassette, Sub-Family B, Member 1; P-gp; PGY-1 Protein; P Glycoprotein; PGY 1 Protein | |
| A 170-kDa transmembrane glycoprotein from the superfamily of ATP-BINDING CASSETTE TRANSPORTERS. It serves as an ATP-dependent efflux pump for a variety of chemicals, including many ANTINEOPLASTIC AGENTS. Overexpression of this glycoprotein is associated with multidrug resistance (see DRUG RESISTANCE, MULTIPLE). | |