POU Domain Factors

POU Proteins; Pit-Oct-Unc Proteins; Transcription Factor POU; POU, Transcription Factor; Pit Oct Unc Proteins
A family of transcription factors characterized by the presence of a bipartite DNA-binding domain known as the POU domain. The POU domain contains two subdomains, a POU-specific domain and a POU-homeodomain. The POU domain was originally identified as a region of approximately 150 amino acids shared between the Pit-1, Oct-1, Oct-2, and Unc-86 transcription factors.