Parathyroid Hormone-Related Protein

Hypercalcemic Hormone of Malignancy; PTH Like Tumor Factor; PTH-Like Protein; PTH-Related Peptide; PTHrP; Parathyroid Hormone Like Tumor Factor; Parathyroid Hormone-Like Protein; Parathyroid Hormone-Related Peptide; Tumor Hypercalcemic Factor
A ubiquitously expressed, secreted protein with bone resorption and renal calcium reabsorption activities that are similar to PARATHYROID HORMONE. It does not circulate in appreciable amounts in normal subjects, but rather exerts its biological actions locally. Overexpression of parathyroid hormone-related protein by tumor cells results in humoral calcemia of malignancy.