Phosphatidylcholine-Sterol O-Acyltransferase |
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| Cholesterol Ester Lysolecithin Acyltransferase; Phosophatidylcholine-Sterol Acyltransferase; Acyltransferase, Lecithin; Acyltransferase, Lecithin Cholesterol; Acyltransferase, Phosophatidylcholine-Sterol; Cholesterol Acyltransferase, Lecithin | |
| An enzyme secreted from the liver into the plasma of many mammalian species. It catalyzes the esterification of the hydroxyl group of lipoprotein cholesterol by the transfer of a fatty acid from the C-2 position of lecithin. In familial lecithin:cholesterol acyltransferase deficiency disease, the absence of the enzyme results in an excess of unesterified cholesterol in plasma. EC 2.3.1.43. | |