Phosphoribosylaminoimidazolecarboxamide Formyltransferase
AICAR Formyltransferase; AICAR Transformylase; AICARTFase; Aminoimidazolecarboxamide Ribonucleotide Transformylase; Formyltransferase, AICAR; Formyltransferase, Phosphoribosylaminoimidazolecarboxamide
An enzyme that catalyzes the conversion of aminoimidazole-4-carboxamide ribonucleotide to 5-formyl-aminoimidazole-4-carboxamide ribonucleotide in the PURINE de novo synthesis pathway. It requires the cofactor N(10)-FORMYLTETRAHYDROFOLATE as the formyl donor.