Pregnancy-Associated alpha 2-Macroglobulins
PAAG; alpha(2)-PAG; alpha2-PAG; Pregnancy Associated alpha 2 Globulins; Pregnancy Associated alpha 2 Glycoproteins; Pregnancy Associated alpha 2 Macroglobulins; alpha 2-Globulins, Pregnancy-Associated; alpha 2-Glycoproteins, Pregnancy-Associated
Large (>160 kDa) glycoproteins with electrophoretic mobility of ALPHA-GLOBULINS, found in high concentration in the plasma of pregnant women but also in a number of species including mouse, rat, and others (ALPHA-MACROGLOBULINS). In humans, they are always present in the circulation and are nonspecific inhibitors of PROTEINASES, similar to COMPLEMENT PROTEINS (C3; C4; C5).