Protein Inhibitors of Activated STAT |
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| PIAS Proteins; PIAS1 Protein; PIAS2 Protein Inhibitor of Activated STAT; PIAS3 Protein Inhibitor of Activated STAT; PIAS4 Protein Inhibitor of Activated STAT | |
| A family of structurally related proteins that are constitutively expressed and that negatively regulate cytokine-mediated SIGNAL TRANSDUCTION PATHWAYS. PIAS proteins inhibit the activity of SIGNAL TRANSDUCERS AND ACTIVATORS OF TRANSCRIPTION. | |