Proto-Oncogene Proteins c-bcr definition

Proto-Oncogene Proteins c-bcr
Breakpoint Cluster Region Protein; Proto-Oncogene Protein bcr; Proto-Oncogene Protein c-bcr; c-bcr Proto-Oncogene Proteins; Proteins, c-bcr; Proto Oncogene Protein bcr; Proto Oncogene Protein c bcr; Proto Oncogene Proteins c bcr
Proto-oncogene protein bcr is a serine-threonine kinase that functions as a negative regulator of CELL PROLIFERATION and NEOPLASTIC CELL TRANSFORMATION. It is commonly fused with cellular abl protein to form BCR-ABL FUSION PROTEINS in PHILADELPHIA CHROMOSOME positive LEUKEMIA patients.