Proto-Oncogene Proteins c-met |
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| Receptor, HGF; Receptor, Hepatocyte Growth Factor; Receptor, Scatter Factor; Scatter Factor Receptor; Proto Oncogene Proteins c met; Proto-Oncogene Proteins, met; c met Proteins; met Proto Oncogene Proteins | |
| Cell surface protein-tyrosine kinase receptors for HEPATOCYTE GROWTH FACTOR. They consists of an extracellular alpha chain which is disulfide-linked to the transmembrane beta chain. The cytoplasmic portion contains the catalytic domain and sites critical for the regulation of kinase activity. Mutations of the gene for PROTO-ONCOGENE PROTEINS C-MET are associated with papillary renal carcinoma and other neoplasia. | |