Proto-Oncogene Proteins c-rel definition

Proto-Oncogene Proteins c-rel
Proto-Oncogene Products c-rel; Proto-Oncogene Protein c-rel; Proto-Oncogene Proteins rel; c-rel Protein; p68 c-rel; rel Proto-Oncogene Product p68; Protein, c-rel; Proteins, c-rel; Proto Oncogene Products c rel; Proto Oncogene Protein c rel
Cellular DNA-binding proteins encoded by the rel gene (GENES, REL). They are expressed predominately in hematopoietic cells and may play a role in lymphocyte differentiation. Rel frequently combines with other related proteins (NF-KAPPA B, I-kappa B, relA) to form heterodimers that regulate transcription. Rearrangement or overexpression of c-rel can cause tumorigenesis.