Pulmonary Surfactant-Associated Protein A definition

Pulmonary Surfactant-Associated Protein A
SP-A Protein; Surfactant Protein A; Pulmonary Surfactant Associated Protein A; SP A Protein
An abundant pulmonary surfactant-associated protein that binds to a variety of lung pathogens, resulting in their opsinization. It also stimulates MACROPHAGES to undergo PHAGOCYTOSIS of microorganisms. Surfactant protein A contains a N-terminal collagen-like domain and a C-terminal lectin domain that are characteristic of members of the collectin family of proteins.