Pyroglutamyl-Peptidase I

Pyroglutamyl-Peptide Hydrolase; 5 Oxoprolyl Peptidase; Aminopeptidase, Pyroglutamate; I, Pyroglutamyl-Peptidase; Peptidase, Pyrrolidonecarboxylate; Peptidase, Pyrrolidonyl; Pyroglutamyl Peptidase I; Pyroglutamyl Peptide Hydrolase
An enzyme that catalyzes the release of a N-terminal pyroglutamyl group from a polypeptide provided the next residue is not proline. It is inhibited by thiol-blocking reagents and occurs in mammalian tissues, microorganisms, and plants. (From Enzyme Nomenclature, 1992) EC 3.4.19.3.