RNA Interference |
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| Posttranscriptional Gene Silencing; RNA Silencing; Gene Silencing, Post Transcriptional; Gene Silencing, Posttranscriptional; Gene Silencings, Post-Transcriptional; Gene Silencings, Posttranscriptional; Interference, RNA; Interferences, RNA | |
| A gene silencing phenomenon whereby specific dsRNAs (RNA, DOUBLE-STRANDED) trigger the degradation of homologous mRNA (RNA, MESSENGER). The specific dsRNAs are processed into SMALL INTERFERING RNA (siRNA) which serves as a guide for cleavage of the homologous mRNA in the RNA-INDUCED SILENCING COMPLEX (RISC). DNA METHYLATION may also be triggered during this process. | |