RNA-Induced Silencing Complex

RISC Multicomponent Nuclease; Complex, RNA-Induced Silencing; Multicomponent Nuclease, RISC; Nuclease, RISC Multicomponent; RNA Induced Silencing Complex; Silencing Complex, RNA-Induced
A multicomponent, ribonucleoprotein complex that cleaves specific mRNAs (RNA, MESSENGER) which are targeted for degradation by homologous dsRNAs (RNA, DOUBLE-STRANDED) during the process of RNA INTERFERENCE. It includes siRNA (RNA, SMALL INTERFERING) that is generated from the specific dsRNA.